【摘要】 子宫内膜异位症(EMs)是妇科常见疾病之一,该病在病理上呈良性形态学改变,但具有类似恶性肿瘤的种植、侵袭及远处转移能力。EMs是一种雌激素依赖性疾病,CYP19基因的表达与雌激素的产生密切相关,其突变可能会改变雌激素的暴露情况,影响EMs的发病风险。目前关于CYP19基因多态性与EMs之间的关系仍存在争论,尚需深入研究以明确芳香化酶的基因多态性在EMs发生中的作用。 更多还原

【Abstract】 Endometriosis(EMs) is one of the common gynecological diseases,the pathology showed benign morphological changes of but with a similar malignant tumors characteristics of planting,erosion and distant metastasis.EMs is an estrogen-dependent diseases,CYP 19 gene expression is closely related to the production of estrogen,and its mutations may alter estrogen exposure,thereby affecting the pathogenesis of endometriosis.Currently on the CYP 19 gene polymorphism and the relationship between EMs are st... 更多还原