Mast Cell Stabilizing,Antianaphylactic and Antihistaminic Activity of Coccinia grandis Fruits in Asthma

中国天然药物 , Chinese Journal of Natural Medicines,
编辑部邮箱 , 2011年05期 【作者】 Dnyaneshwar J Taur； Ravindra Y Patil；

【Author】 Dnyaneshwar J Taur1,Ravindra Y Patil21Department of Pharmacognosy,SVPM’s College of Pharmacy,Malegaon(bk),Baramati-413115,Maharashtra,India;2Department of Pharmacognosy,PDEA’s SU College of Pharmaceutical Sciences and Research Center,Kharadi,Pune-411014,Maharashtra,India

【机构】 Department of Pharmacognosy,SVPM’s College of Pharmacy,Malegaon(bk),Baramati-413115,Maharashtra,India； Department of Pharmacognosy,PDEA’s SU College of Pharmaceutical Sciences and Research Center,Kharadi,Pune-411014,Maharashtra,India；

【摘要】 Coccinia grandis Linn(Curcubitaceae) is a climber herb cultivated throughout India.In traditional medicine fruits have been used to treat leprosy,fever,asthma,bronchitis and jaundice.In present study,ethanol extract of C.grandis fruit(ECGF) at 100,125 and 150 mg·kg-1,i.p.,was evaluated for mast cell stabilizing,antianaphylactic and antihistaminic activity using egg albumin induced mast cell degranulation in mice;passive cutaneous anaphylaxis in rats and clonidine induced catalepsy in mice respec... 更多还原

【Abstract】 Coccinia grandis Linn(Curcubitaceae) is a climber herb cultivated throughout India.In traditional medicine fruits have been used to treat leprosy,fever,asthma,bronchitis and jaundice.In present study,ethanol extract of C.grandis fruit(ECGF) at 100,125 and 150 mg·kg-1,i.p.,was evaluated for mast cell stabilizing,antianaphylactic and antihistaminic activity using egg albumin induced mast cell degranulation in mice;passive cutaneous anaphylaxis in rats and clonidine induced catalepsy in mice respec... 更多还原
【关键词】 Coccinia grandis； Allergy； Asthma； Clonidine； Mast cell degranulations；
【Key words】 Coccinia grandis； Allergy； Asthma； Clonidine； Mast cell degranulations；
【分类号】R285

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