Effect of Salvia officinalis Hydroalcoholic Extract on Vincristine-induced Neuropathy in Mice

中国天然药物 , Chinese Journal of Natural Medicines,
编辑部邮箱 , 2011年05期 【作者】 Ali Namvaran Abbas Abad； Mir Hadi Khayate Nouri； Farzaneh Tavakkoli；

【Author】 Ali Namvaran Abbas Abad1,Mir Hadi Khayate Nouri2,Farzaneh Tavakkoli1 1 Young Researchers Club,Tabriz Branch,Islamic Azad University,Tabriz,Iran;2Department of Pharmacology & Toxicology,Faculty of Veterinary Medicine,Tabriz Branch,Islamic Azad University,Tabriz-Iran Pharmacology & Toxicology De-partment,Veterinary Faculty of Islamic Azad University,Tabriz branch,Tabriz-Iran

【机构】 Young Researchers Club,Tabriz Branch,Islamic Azad University,Tabriz,Iran； Pharmacology & Toxicology Department,Veterinary Faculty of Islamic Azad University,Tabriz branch,Tabriz-Iran； Department of Pharmacology & Toxicology,Faculty of Veterinary Medicine,Tabriz Branch,Islamic Azad University,Tabriz-Iran；

【摘要】 AIM:Vincristine is one of the most commonly used chemotherapeutic drugs to treat a variety of malignant diseases,including leukemia and lymphoma.Studies have shown that vincristine cause painful effects,whereas Salvia officinalis(SO) showed analgesic and anti-inflammatory effects.The aim of this study is to investigate the effects of the SO hydro-alcoholic extract on vincristine-induced peripheral neuropathy in mice in comparison with morphine.METHODS:Experiments were performed on 60 NMRI male m... 更多还原

【Abstract】 AIM:Vincristine is one of the most commonly used chemotherapeutic drugs to treat a variety of malignant diseases,including leukemia and lymphoma.Studies have shown that vincristine cause painful effects,whereas Salvia officinalis(SO) showed analgesic and anti-inflammatory effects.The aim of this study is to investigate the effects of the SO hydro-alcoholic extract on vincristine-induced peripheral neuropathy in mice in comparison with morphine.METHODS:Experiments were performed on 60 NMRI male m... 更多还原
【关键词】 Salvia officinalis； Vincristine； Pain； Morphine； Mice；
【Key words】 Salvia officinalis； Vincristine； Pain； Morphine； Mice；
【分类号】R285.5

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