【作者】 李瑾; 郑宏;
【Author】 LI Jin,ZHENG Hong Department of Anesthesia,the First Hospital,Xinjiang Medical University,Xin Jiang 830054,China
【机构】 新疆医科大学第一附属医院麻醉科;
【摘要】 目的系统评价冠脉旁路移植术术后心肌损伤标记物对术后短期、长期死亡率的影响。方法计算机检索Cochrane Library、PubMed、EMbase、Ovid、CNKI、VIP、WanFang Data,检索时间均从建库至2011年8月,手工检索相关杂志并追索纳入文献的参考文献。纳入冠脉旁路移植术后心肌损伤标记物[肌酸激酶同工酶(CK-MB)和肌钙蛋白I(cTnI)]对术后死亡率影响的队列和病例对照研究,由两位评价员按照纳入排除标准独立进行资料提取、质量评价并交叉核对后,采用RevMan 5.0软件进行Meta分析。结果纳入10个队列研究,共10 793例患者。Meta分析结果显示:无论体外循环冠脉搭桥术(on-pump)或非体外循环冠脉搭桥术(o pump),CK-MB增高组术后短期死亡率均比CK-MB非增高组高,两组差异有统计学意义[RR=2.88,95%CI(1.94,4.28),P<0.000 01;RR=3.64,95%CI(1.07,12.42),P=0.04]。无论on-pump或o pump,CK-MB增高组术后长期死亡率均比CK-MB非增高组高,两组差异有统计学... 更多还原
【Abstract】 Objective To evaluate the influences of myocardial injury markers on the short-term and long-term mortality after coronary artery bypass grafting(CABG),so as to provide valuable references for clinical prognosis assessment.Methods Literature was electronically searched in CBM,PubMed,OVID,EMbase and CNKI from the date of their establishment to August 2011,meanwhile the manual searches were also performed to systemize the papers.According to the Cochrane Handbook for systematic reviews,the studies... 更多还原 【关键词】 冠脉移植旁路术; 心肌损伤标记物; 肌酸激酶同工酶; 肌钙蛋白I; Meta分析; 【Key words】 Coronary artery bypass grafting; Myocardial injury markers; Creatine kinase-myocardial band(CK-MB); Cardiac troponin I(cTnI); Meta-analysis;
【分类号】R654.2
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