当归补血汤含药血清对高糖条件下肾小球系膜细胞增殖的影响 Effect of Angelicae Sinensis Decoction for Supplementing Blood-containing Serum on Proliferation of Glomerular Mesangial Cell under High Glucose推荐 CAJ下载 PDF下载 不支持迅雷等下载工具,请取消加速工具后下载。
中西医结合研究 , Research of Integrated Traditional Chinese and Western Medicine, 编辑部邮箱 , 2011年04期 【作者】 龚宇; 张莹雯;
【Author】 GONG Yu,ZHANG Yingwen Department of Integrated Traditional Chinese and Western Medicine,Zhongnan Hospitial,Wuhan University,Wuhan 430071,China
【机构】 武汉大学中南医院中西医结合科;
【摘要】 目的观察当归补血汤含药血清对高糖条件下肾小球系膜细胞(GMC)增殖的影响,探讨其在糖尿病肾病(DN)防治中的意义。方法采用四甲基偶氮唑蓝(MTT)比色法动态观察各种处理因素的作用下GMC增殖情况。结果高糖能明显刺激体外培养的GMC增殖,而当归补血汤能明显抑制GMC增殖,并呈一定量效关系,即随糖或药物浓度的增加,GMC增殖也相应增加或减少。结论高糖可促进GMC增殖,当归补血汤能明显抑制高糖条件下GMC增殖,从而发挥预防和延缓DN发展的积极作用。 更多还原
【Abstract】 Objective To investigate the effect of Angelicae Sinensis Decoction for Supplementing Blood-containing serum(one kind of traditional prescription of Chinese herbs)on the proliferation of glomerular mesangial cells(GMC)which were cultured under high glucose condition.Methods Use colorimetric method of methyl thiazolyl tetrazolium to observe the proliferation of glomerular mesangial cell in various kinds of factors.Results GMC cultured in vitro obviously proliferated under the stimulation of high ... 更多还原 【关键词】 当归补血汤; 系膜细胞; 糖尿病肾病; 【Key words】 Angelicae Sinensis Decoction for Supplementing Blood; glomerular mesangial cells; diabetic nephropathy; 【基金】 国家自然科学基金课题(No.30973819)【分类号】R285.5
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